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Psoralen and Ultraviolet A Light Treatment Directly Affects Phosphatidylinositol 3-Kinase Signal Transduction by Altering Plasma Membrane Packing

Psoralen and ultraviolet A light (PUVA) are used to kill pathogens in blood products and as a treatment of aberrant cell proliferation in dermatitis, cutaneous T-cell lymphoma, and graft-versus-host disease. DNA damage is well described, but the direct effects of PUVA on cell signal transduction are...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Van Aelst, Britt, Devloo, Rosalie, Zachée, Pierre, t'Kindt, Ruben, Sandra, Koen, Vandekerckhove, Philippe, Compernolle, Veerle, Feys, Hendrik B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5114394/
https://ncbi.nlm.nih.gov/pubmed/27687726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.735126
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