Pharmacokinetic and pharmacodynamic study of doxorubicin in children with cancer: results of a “European Pediatric Oncology Off-patents Medicines Consortium” trial

PURPOSE: Doxorubicin is a key component in many pediatric oncology treatment regimens; still pharmacology data on which current dosing regimens are based are very limited. METHODS: We conducted a multinational pharmacokinetic study investigating age dependency of doxorubicin metabolism and eliminati...

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Detalhes bibliográficos
Publicado no:Cancer Chemother Pharmacol
Main Authors: Krischke, Miriam, Hempel, Georg, Völler, Swantje, André, Nicolas, D’Incalci, Maurizio, Bisogno, Gianni, Köpcke, Wolfgang, Borowski, Matthias, Herold, Ralf, Boddy, Alan V., Boos, Joachim
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2016
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5114325/
https://ncbi.nlm.nih.gov/pubmed/27770238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00280-016-3174-8
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