Mammalian-Specific Central Myelin Protein Opalin Is Redundant for Normal Myelination: Structural and Behavioral Assessments

Opalin, a central nervous system-specific myelin protein phylogenetically unique to mammals, has been suggested to play a role in mammalian-specific myelin. To elucidate the role of Opalin in mammalian myelin, we disrupted the Opalin gene in mice and analyzed the impacts on myelination and behavior....

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Publicat a:PLoS One
Autors principals: Yoshikawa, Fumio, Sato, Yumi, Tohyama, Koujiro, Akagi, Takumi, Furuse, Tamio, Sadakata, Tetsushi, Tanaka, Mika, Shinoda, Yo, Hashikawa, Tsutomu, Itohara, Shigeyoshi, Sano, Yoshitake, Ghandour, M. Said, Wakana, Shigeharu, Furuichi, Teiichi
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2016
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5113975/
https://ncbi.nlm.nih.gov/pubmed/27855200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0166732
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