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Characterization of a vraG Mutant in a Genetically Stable Staphylococcus aureus Small-Colony Variant and Preliminary Assessment for Use as a Live-Attenuated Vaccine against Intrammamary Infections

Staphylococcus aureus is a leading cause of bovine intramammary infections (IMIs) that can evolve into difficult-to-treat chronic mastitis. To date, no vaccine formulation has shown high protective efficacy against S. aureus IMI, partly because this bacterium can efficiently evade the immune system....

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Côté-Gravel, Julie, Brouillette, Eric, Obradović, Nataša, Ster, Céline, Talbot, Brian G., Malouin, François
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5113970/
https://ncbi.nlm.nih.gov/pubmed/27855187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0166621
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