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Loss of neurokinin-1 receptor alters ocular surface homeostasis and promotes an early development of herpes stromal keratitis

Substance P neuropeptide and its receptor neurokinin-1 (NK1R) are reported to present on the ocular surface. In this study, mice lacking functional NK1R exhibited an excessive desquamation of apical corneal epithelial cells in association with an increased epithelial cell proliferation, increased ep...

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Bibliografski detalji
Izdano u:J Immunol
Glavni autori: Gaddipati, Subhash, Rao, Pushpa, Jerome, Andrew David, Burugula, Bala Bharathi, Gerard, Norma P, Suvas, Susmit
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5113833/
https://ncbi.nlm.nih.gov/pubmed/27798158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1600836
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