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Gold‐Induced Fibril Growth: The Mechanism of Surface‐Facilitated Amyloid Aggregation

The question of how amyloid fibril formation is influenced by surfaces is crucial for a detailed understanding of the process in vivo. We applied a combination of kinetic experiments and molecular dynamics simulations to elucidate how (model) surfaces influence fibril formation of the amyloid‐formin...

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Publicat a:Angew Chem Int Ed Engl
Autors principals: Gladytz, Anika, Abel, Bernd, Risselada, Herre Jelger
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2016
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5113782/
https://ncbi.nlm.nih.gov/pubmed/27513605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201605151
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