Hepatocellular carcinoma redirects to ketolysis for progression under nutrition deprivation stress

Cancer cells are known for their capacity to rewire metabolic pathways to support survival and proliferation under various stress conditions. Ketone bodies, though produced in the liver, are not consumed in normal adult liver cells. We find here that ketone catabolism or ketolysis is re-activated in...

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Detalhes bibliográficos
Publicado no:Cell Res
Main Authors: Huang, De, Li, Tingting, Wang, Lin, Zhang, Long, Yan, Ronghui, Li, Kui, Xing, Songge, Wu, Gongwei, Hu, Lan, Jia, Weidong, Lin, Sheng-Cai, Dang, Chi V, Song, Libing, Gao, Ping, Zhang, Huafeng
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5113304/
https://ncbi.nlm.nih.gov/pubmed/27644987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2016.109
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