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Unmasking the U2AF homology motif family: a bona fide protein–protein interaction motif in disguise

U2AF homology motifs (UHM) that recognize U2AF ligand motifs (ULM) are an emerging family of protein–protein interaction modules. UHM–ULM interactions recur in pre-mRNA splicing factors including U2AF1 and SF3b1, which are frequently mutated in myelodysplastic syndromes. The core topology of the UHM...

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Detalhes bibliográficos
Publicado no:RNA
Main Authors: Loerch, Sarah, Kielkopf, Clara L.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5113200/
https://ncbi.nlm.nih.gov/pubmed/27852923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.057950.116
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