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Expressions of the low density lipoprotein receptor and 3-hydroxy-3-methylglutaryl coenzyme A reductase genes are stimulated by recombinant platelet-derived growth factor isomers.

The plausible role that platelet-derived growth factor (PDGF) has in the localized pathophysiological changes that occur in the arterial wall during development of atherosclerotic lesions led us to investigate the influence of recombinant (r)PDGF isomers -AA, -AB, and -BB on the expression of low de...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Roth, M, Emmons, L R, Perruchoud, A, Block, L H
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1991
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC51131/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2000393/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.5.1888
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