Development of an Attenuated Tat Protein as a Highly-effective Agent to Specifically Activate HIV-1 Latency

Although combined antiretroviral therapy (cART) successfully decreases plasma viremia to undetectable levels, the complete eradication of human immunodeficiency virus type 1 (HIV-1) remains impractical because of the existence of a viral reservoir, mainly in resting memory CD4(+) T cells. Various cy...

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Bibliographic Details
Published in:Mol Ther
Main Authors: Geng, Guannan, Liu, Bingfeng, Chen, Cancan, Wu, Kang, Liu, Jun, Zhang, Yijun, Pan, Ting, Li, Jun, Yin, Yue, Zhang, Junsong, Huang, Feng, Yu, Fei, Chen, Jingliang, Ma, Xiancai, Zhou, Jie, Kuang, Ersheng, Liu, Chao, Cai, Weiping, Zhang, Hui
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2016
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5113098/
https://ncbi.nlm.nih.gov/pubmed/27434587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2016.117
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