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Too much of a good thing: Sustained type 1 interferon signaling limits humoral responses to secondary viral infection

The induction of a pan-immunosuppressive state is a central feature of persistent viral infections. Over the past decade, multiple pathways have been identified that contribute to immune suppression. Recently, it was revealed that aberrant/sustained type 1 interferon (IFN-I) production/signaling is...

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Publicado en:Eur J Immunol
Autor Principal: Teijaro, John R.
Formato: Artigo
Idioma:Inglês
Publicado: 2016
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5113021/
https://ncbi.nlm.nih.gov/pubmed/26783074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201546224
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