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Mutation of the Streptococcus gordonii Thiol-Disulfide Oxidoreductase SdbA Leads to Enhanced Biofilm Formation Mediated by the CiaRH Two-Component Signaling System

Streptococcus gordonii is a commensal inhabitant of human oral biofilms. Previously, we identified an enzyme called SdbA that played an important role in biofilm formation by S. gordonii. SdbA is thiol-disulfide oxidoreductase that catalyzes disulfide bonds in secreted proteins. Surprisingly, inacti...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Davey, Lauren, Halperin, Scott A., Lee, Song F.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5112981/
https://ncbi.nlm.nih.gov/pubmed/27846284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0166656
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