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Assessment of Intrathecal Free Light Chain Synthesis: Comparison of Different Quantitative Methods with the Detection of Oligoclonal Free Light Chains by Isoelectric Focusing and Affinity-Mediated Immunoblotting

OBJECTIVES: We aimed to compare various methods for free light chain (fLC) quantitation in cerebrospinal fluid (CSF) and serum and to determine whether quantitative CSF measurements could reliably predict intrathecal fLC synthesis. In addition, we wished to determine the relationship between free ka...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Zeman, David, Kušnierová, Pavlína, Švagera, Zdeněk, Všianský, František, Byrtusová, Monika, Hradílek, Pavel, Kurková, Barbora, Zapletalová, Olga, Bartoš, Vladimír
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5112955/
https://ncbi.nlm.nih.gov/pubmed/27846293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0166556
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