Chromosomal Instability Estimation Based on Next Generation Sequencing and Single Cell Genome Wide Copy Number Variation Analysis

Genomic instability is a hallmark of cancer often associated with poor patient outcome and resistance to targeted therapy. Assessment of genomic instability in bulk tumor or biopsy can be complicated due to sample availability, surrounding tissue contamination, or tumor heterogeneity. The Epic Scien...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:PLoS One
Main Authors: Greene, Stephanie B., Dago, Angel E., Leitz, Laura J., Wang, Yipeng, Lee, Jerry, Werner, Shannon L., Gendreau, Steven, Patel, Premal, Jia, Shidong, Zhang, Liangxuan, Tucker, Eric K., Malchiodi, Michael, Graf, Ryon P., Dittamore, Ryan, Marrinucci, Dena, Landers, Mark
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2016
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5112954/
https://ncbi.nlm.nih.gov/pubmed/27851748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0165089
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