Chromosomal Instability Estimation Based on Next Generation Sequencing and Single Cell Genome Wide Copy Number Variation Analysis

Genomic instability is a hallmark of cancer often associated with poor patient outcome and resistance to targeted therapy. Assessment of genomic instability in bulk tumor or biopsy can be complicated due to sample availability, surrounding tissue contamination, or tumor heterogeneity. The Epic Scien...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Greene, Stephanie B., Dago, Angel E., Leitz, Laura J., Wang, Yipeng, Lee, Jerry, Werner, Shannon L., Gendreau, Steven, Patel, Premal, Jia, Shidong, Zhang, Liangxuan, Tucker, Eric K., Malchiodi, Michael, Graf, Ryon P., Dittamore, Ryan, Marrinucci, Dena, Landers, Mark
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5112954/
https://ncbi.nlm.nih.gov/pubmed/27851748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0165089
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