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Comprehensive screening of target molecules by next-generation sequencing in patients with malignant solid tumors: guiding entry into phase I clinical trials

It is still controversial whether comprehensive genome screening of target molecules by next generation sequencing (NGS) is needed to increase clinical efficacy of investigational drugs or accelerate drug development, although several studies are being carried out. Therefore, we performed a prospect...

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Detalhes bibliográficos
Publicado no:Mol Cancer
Main Authors: Tanabe, Yuko, Ichikawa, Hitoshi, Kohno, Takashi, Yoshida, Hiroshi, Kubo, Takashi, Kato, Mamoru, Iwasa, Satoru, Ochiai, Atsushi, Yamamoto, Noboru, Fujiwara, Yasuhiro, Tamura, Kenji
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5112718/
https://ncbi.nlm.nih.gov/pubmed/27852271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-016-0553-z
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