Effect of cessation of GH treatment on cognition during transition phase in Prader-Willi syndrome: results of a 2-year crossover GH trial

BACKGROUND: Patients with Prader-Willi syndrome (PWS) have a cognitive impairment. Growth hormone (GH) treatment during childhood improves cognitive functioning, while cognition deteriorates in GH-untreated children with PWS. Cessation of GH treatment at attainment of adult height (AH) might deterio...

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Detalhes bibliográficos
Publicado no:Orphanet J Rare Dis
Main Authors: Kuppens, R. J., Mahabier, E. F., Bakker, N. E., Siemensma, E. P. C., Donze, S. H., Hokken-Koelega, A. C. S.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5112648/
https://ncbi.nlm.nih.gov/pubmed/27852283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13023-016-0535-7
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