E-cadherin genetic variants predict survival outcome in breast cancer patients

BACKGROUND: E-cadherin is a major component of adherens junctions that regulates cell shape and maintains tissue integrity. A complete loss or any decrease in cell surface expression of E-cadherin will interfere with the cell-to-cell junctions’ strength and leads to cell detachment and escape from t...

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Bibliografische gegevens
Gepubliceerd in:J Transl Med
Hoofdauteurs: Memni, Hager, Macherki, Yosra, Klayech, Zahra, Ben-Haj-Ayed, Ahlem, Farhat, Karim, Remadi, Yassmine, Gabbouj, Sallouha, Mahfoudh, Wijden, Bouzid, Nadia, Bouaouina, Noureddine, Chouchane, Lotfi, Zakhama, Abdelfattah, Hassen, Elham
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2016
Onderwerpen:
Research
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5112645/
https://ncbi.nlm.nih.gov/pubmed/27852262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-016-1077-4
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