Loss of NMDA receptors in dopamine neurons leads to the development of affective disorder-like symptoms in mice

The role of changes in dopamine neuronal activity during the development of symptoms in affective disorders remains controversial. Here, we show that inactivation of NMDA receptors on dopaminergic neurons in adult mice led to the development of affective disorder-like symptoms. The loss of NMDA rece...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Jastrzębska, Kamila, Walczak, Magdalena, Cieślak, Przemysław Eligiusz, Szumiec, Łukasz, Turbasa, Mateusz, Engblom, David, Błasiak, Tomasz, Parkitna, Jan Rodriguez
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5112557/
https://ncbi.nlm.nih.gov/pubmed/27853270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep37171
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