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Loss of NMDA receptors in dopamine neurons leads to the development of affective disorder-like symptoms in mice

The role of changes in dopamine neuronal activity during the development of symptoms in affective disorders remains controversial. Here, we show that inactivation of NMDA receptors on dopaminergic neurons in adult mice led to the development of affective disorder-like symptoms. The loss of NMDA rece...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Sci Rep
Egile Nagusiak: Jastrzębska, Kamila, Walczak, Magdalena, Cieślak, Przemysław Eligiusz, Szumiec, Łukasz, Turbasa, Mateusz, Engblom, David, Błasiak, Tomasz, Parkitna, Jan Rodriguez
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 2016
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5112557/
https://ncbi.nlm.nih.gov/pubmed/27853270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep37171
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