Glucocorticoids increase skeletal muscle NF‐κB inducing kinase (NIK): links to muscle atrophy

Glucocorticoids (GC) are a frontline therapy for numerous acute and chronic diseases because of their demonstrated efficacy at reducing systemic inflammation. An unintended side effect of GC therapy is the stimulation of skeletal muscle atrophy. Pathophysiological mechanisms responsible for GC‐induc...

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Dettagli Bibliografici
Pubblicato in:Physiol Rep
Autori principali: Fry, Christopher S., Nayeem, Syed Z., Dillon, Edgar L., Sarkar, Partha S., Tumurbaatar, Batbayar, Urban, Randall J., Wright, Traver J., Sheffield‐Moore, Melinda, Tilton, Ronald G., Choudhary, Sanjeev
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2016
Soggetti:
Original Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5112493/
https://ncbi.nlm.nih.gov/pubmed/27905294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.13014
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