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Immunomodulatory functions of BTLA and HVEM govern induction of extrathymic regulatory T cells and tolerance by dendritic cells

Dendritic cells (DCs) initiate immunity and also antigen-specific tolerance mediated by extrathymic regulatory T (Treg) cells. Yet it remains unclear how DCs regulate induction of such tolerance. Here we report that efficient induction of Treg cells was instructed by BTLA(+)DEC205(+)CD8(+)CD11c(+) D...

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Bibliografische gegevens
Gepubliceerd in:Immunity
Hoofdauteurs: Jones, Andrew, Bourque, Jessica, Kuehm, Lindsey, Opejin, Adeleye, Teague, Ryan M., Gross, Cindy, Hawiger, Daniel
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2016
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5112132/
https://ncbi.nlm.nih.gov/pubmed/27793593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2016.10.008
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