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The Mutation Profile of Calreticulin in Patients with Myeloproliferative Neoplasms and Acute Leukemia

OBJECTIVE: Calreticulin (CALR) plays important roles in cell proliferation, apoptosis, and immune responses. CALR mutations were described recently in Janus kinase 2 gene (JAK2)-negative or MPL-negative primary myelofibrosis (PMF) and essential thrombocythemia (ET) patients. CALR trails JAK2 as the...

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Detalhes bibliográficos
Publicado no:Turk J Haematol
Main Authors: Wang, Jingyi, Hao, Jianguo, He, Na, Ji, Chunyan, Ma, Daoxin
Formato: Artigo
Idioma:Inglês
Publicado em: Galenos Publishing 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5111462/
https://ncbi.nlm.nih.gov/pubmed/26377485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4274/tjh.2015.0220
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