Design, Construction and Evaluation of 1a/JFH1 HCV Chimera by Replacing the Intergenotypic Variable Region

BACKGROUND: The E2 glycoprotein is an important encoded hepatitis C virus (HCV) protein that contains three different variable regions. OBJECTIVES: The aim of the present study was to construct an HCV 1a/JFH1 chimeric virus by replacing the intergenotypic variable region (igVR) fragment of the highl...

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Bibliographic Details
Published in:Hepat Mon
Main Authors: Ghasemi, Faezeh, Ghayour-Mobarhan, Majid, Pasdar, Alireza, Pourianfar, Hamid, Reza Aghasadeghi, Mohammad, Gouklani, Hamed, Meshkat, Zahra
Format: Artigo
Language:Inglês
Published: Kowsar 2016
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5111421/
https://ncbi.nlm.nih.gov/pubmed/27882063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5812/hepatmon.38261
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