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Dynamic regulation of a ribosome rescue pathway in erythroid cells and platelets

Protein synthesis continues in platelets and maturing reticulocytes, although these blood cells lack nuclei and do not make new mRNA or ribosomes. Here, we analyze translation in primary human cells from both anucleate lineages by ribosome profiling and uncover dramatic accumulation of post-terminat...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Mills, Eric W, Wangen, Jamie, Green, Rachel, Ingolia, Nicholas T
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5111367/
https://ncbi.nlm.nih.gov/pubmed/27681415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.08.088
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