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Safety and feasibility of cell-based therapy of autologous bone marrow-derived mononuclear cells in plate-stabilized proximal humeral fractures in humans

BACKGROUND: Local implantation of ex vivo concentrated, washed and filtrated human bone marrow-derived mononuclear cells (BMC) seeded onto β-tricalciumphosphate (TCP) significantly enhanced bone healing in a preclinical segmental defect model. Based on these results, we evaluated in a first clinical...

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Publicat a:J Transl Med
Autors principals: Seebach, Caroline, Henrich, Dirk, Meier, Simon, Nau, Christoph, Bonig, Halvard, Marzi, Ingo
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5111224/
https://ncbi.nlm.nih.gov/pubmed/27846890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-016-1066-7
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