An endogenous caspase-11 ligand elicits interleukin-1 release from living dendritic cells

Dendritic cells (DCs) utilize pattern recognition receptors to detect microorganisms and activate protective immunity. These cells and receptors are thought to operate in an all-or-none manner, existing in an immunologically active or inactive state. Here, we report that encounters with microbial pr...

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Bibliografiske detaljer
Udgivet i:Science
Main Authors: Zanoni, Ivan, Tan, Yunhao, Di Gioia, Marco, Broggi, Achille, Ruan, Jianbin, Shi, Jianjin, Donado, Carlos A, Shao, Feng, Wu, Hao, Springstead, James R., Kagan, Jonathan C.
Format: Artigo
Sprog:Inglês
Udgivet: 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5111085/
https://ncbi.nlm.nih.gov/pubmed/27103670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aaf3036
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