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Two PTP receptors mediate CSPG inhibition by convergent and divergent signaling pathways in neurons

Receptor protein tyrosine phosphatase σ (PTPσ) and its subfamily member LAR act as transmembrane receptors that mediate growth inhibition of chondroitin sulfate proteoglycans (CSPGs). Inhibition of either receptor increases axon growth into and beyond scar tissues after CNS injury. However, it is un...

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Podrobná bibliografie
Vydáno v:Sci Rep
Hlavní autoři: Ohtake, Yosuke, Wong, Daniella, Abdul-Muneer, P. M., Selzer, Michael E., Li, Shuxin
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5111048/
https://ncbi.nlm.nih.gov/pubmed/27849007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep37152
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