Calmodulin-dependent endothelium-derived relaxing factor/nitric oxide synthase activity is present in the particulate and cytosolic fractions of bovine aortic endothelial cells.

Endothelium-derived relaxing factor/nitric oxide (EDRF/NO) synthesized by bovine aortic endothelial cells and subcellular fractions thereof was assayed by its stimulating effect on soluble guanylyl cyclase of rat fetal lung fibroblasts (RFL-6 cells). The release of EDRF/NO by intact endothelial cell...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Förstermann, U, Pollock, J S, Schmidt, H H, Heller, M, Murad, F
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1991
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC51110/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1705708/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.5.1788
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