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Cardiac STAT3 Deficiency Impairs Contractility and Metabolic Homeostasis in Hypertension
Signal transducer and activator of transcription 3 (STAT3) protects the heart from acute ischemic stress. However, the importance of STAT3 to the heart in chronic stress, such as hypertension, is not known. To study this, we used cardiomyocyte-targeted STAT3 knockout (KO) mice and Angiotensin II (AN...
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| Publié dans: | Front Pharmacol |
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| Auteurs principaux: | , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Frontiers Media S.A.
2016
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5110511/ https://ncbi.nlm.nih.gov/pubmed/27899891 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2016.00436 |
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