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Crystal structure of Caenorhabditis elegans HER-1 and characterization of the interaction between HER-1 and TRA-2A

HER-1 is a secreted protein that promotes male development in the nematode Caenorhabditis elegans. HER-1 inhibits the function of TRA-2A, a multipass integral membrane protein thought to serve as its receptor. We report here the 1.5-Å crystal structure of HER-1. The structure was solved by the multi...

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Bibliographische Detailangaben
Hauptverfasser: Hamaoka, Brent Y., Dann, Charles E., Geisbrecht, Brian V., Leahy, Daniel J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2004
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC511037/
https://ncbi.nlm.nih.gov/pubmed/15289613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0402559101
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