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How cholesterol homeostasis is regulated by plasma membrane cholesterol in excess of phospholipids

How do cells sense and control their cholesterol levels? Whereas most of the cell cholesterol is located in the plasma membrane, the effectors of its abundance are regulated by a small pool of cholesterol in the endoplasmic reticulum (ER). The size of the ER compartment responds rapidly and dramatic...

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Bibliografiske detaljer
Main Authors: Lange, Yvonne, Ye, Jin, Steck, Theodore L.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2004
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC511035/
https://ncbi.nlm.nih.gov/pubmed/15289597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0404766101
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