Heme inhibits human immunodeficiency virus 1 replication in cell cultures and enhances the antiviral effect of zidovudine.

The effects of heme alone and heme administered together with 3'-azido-3'-deoxythymidine (AZT) on human immunodeficiency virus replication in human peripheral blood lymphocytes and in the H9 cell line were studied. Heme enhanced the antiviral action of AZT against both drug-resistant and drug-sensit...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Levere, R D, Gong, Y F, Kappas, A, Bucher, D J, Wormser, G P, Abraham, N G
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1991
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC51103/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2000384/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.5.1756
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