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Access to a new class of synthetic building blocks via trifluoromethoxylation of pyridines and pyrimidines

Since the first synthesis of trifluoromethyl ethers in 1935, the trifluoromethoxy (OCF(3)) group has made a remarkable impact in medicinal, agrochemical, and materials science research. However, our inability to facilely incorporate the OCF(3) group into molecules, especially heteroaromatics, has li...

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Detalhes bibliográficos
Publicado no:Chem Sci
Main Authors: Feng, Pengju, Lee, Katarzyna N., Lee, Johnny W., Zhan, Chengbo, Ngai, Ming-Yu
Formato: Artigo
Idioma:Inglês
Publicado em: Royal Society of Chemistry 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5110255/
https://ncbi.nlm.nih.gov/pubmed/27857834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5sc02983j
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