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Thrombomodulin Protects Against Bacterial Keratitis, Is Anti-Inflammatory, but Not Angiogenic

PURPOSE: Thrombomodulin (TM) is a multidomain, transmembrane protein with anti-inflammatory properties. Thrombomodulin domain (D) 1 is lectin-like, interacting with Lewis Y antigen on lipopolysaccharide, and with HMGB1, while TMD23 is associated with angiogenic and anti-inflammatory functions. Thus,...

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Detalhes bibliográficos
Publicado no:Invest Ophthalmol Vis Sci
Main Authors: McClellan, Sharon A., Ekanayaka, Sandamali A., Li, Cui, Jiang, Xiaoyu, Barrett, Ronald P., Hazlett, Linda D.
Formato: Artigo
Idioma:Inglês
Publicado em: The Association for Research in Vision and Ophthalmology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5110241/
https://ncbi.nlm.nih.gov/pubmed/26720461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.15-18393
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