The Respiratory Syncytial Virus Phosphoprotein, Matrix Protein, and Fusion Protein Carboxy-Terminal Domain Drive Efficient Filamentous Virus-Like Particle Formation

Virus-like particles (VLPs) are attractive as a vaccine concept. For human respiratory syncytial virus (hRSV), VLP assembly is poorly understood and appears inefficient. Hence, hRSV antigens are often incorporated into foreign VLP systems to generate anti-RSV vaccine candidates. To better understand...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Meshram, Chetan D., Baviskar, Pradyumna S., Ognibene, Cherie M., Oomens, Antonius G. P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Structure and Assembly
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5110176/
https://ncbi.nlm.nih.gov/pubmed/27654298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01193-16
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