Donor pretreatment with carbon monoxide prevents ischemia/reperfusion injury following heart transplantation in rats

Because inhaled carbon monoxide (CO) provides potent anti-inflammatory and antioxidant effects against ischemia reperfusion injury, we hypothesized that treatment of organ donors with inhaled CO would decrease graft injury after heart transplantation. Hearts were heterotopically transplanted into sy...

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Veröffentlicht in:Med Gas Res
Hauptverfasser: Fujisaki, Noritomo, Kohama, Keisuke, Nishimura, Takeshi, Yamashita, Hayato, Ishikawa, Michiko, Kanematsu, Akihiro, Yamada, Taihei, Lee, Sungsoo, Yumoto, Tetsuya, Tsukahara, Kohei, Kotani, Joji, Nakao, Atsunori
Format: Artigo
Sprache:Inglês
Veröffentlicht: Medknow Publications & Media Pvt Ltd 2016
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5110145/
https://ncbi.nlm.nih.gov/pubmed/27867479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/2045-9912.191357
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