Cleavage of the membrane precursor for transforming growth factor alpha is a regulated process.
Transforming growth factor alpha (TGF-alpha) is generated by cleavage of a membrane-anchored precursor protein, proTGF-alpha. ProTGF-alpha is cleaved at a slow rate and accumulates on the cell surface, thereby mediating cell-cell adhesion and mitogenic stimulation. We show here that cleavage of memb...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1991
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC51097/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2000380/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.5.1726 |
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