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Cleavage of the membrane precursor for transforming growth factor alpha is a regulated process.

Transforming growth factor alpha (TGF-alpha) is generated by cleavage of a membrane-anchored precursor protein, proTGF-alpha. ProTGF-alpha is cleaved at a slow rate and accumulates on the cell surface, thereby mediating cell-cell adhesion and mitogenic stimulation. We show here that cleavage of memb...

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Detalhes bibliográficos
Main Authors: Pandiella, A, Massagué, J
Formato: Artigo
Idioma:Inglês
Publicado em: 1991
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC51097/
https://ncbi.nlm.nih.gov/pubmed/2000380
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