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Characterization of the terminal regions of hepatitis C viral RNA: identification of conserved sequences in the 5' untranslated region and poly(A) tails at the 3' end.

We have determined the nucleotide sequence at the extreme 5' and 3' termini of the hepatitis C virus (HCV) genome. Our analyses of these sequences show (i) the nucleotide sequence in the 5' untranslated region is highly conserved among HCV isolates of widely varying geographical origi...

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Bibliographic Details
Main Authors: Han, J H, Shyamala, V, Richman, K H, Brauer, M J, Irvine, B, Urdea, M S, Tekamp-Olson, P, Kuo, G, Choo, Q L, Houghton, M
Format: Artigo
Language:Inglês
Published: 1991
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC51094/
https://ncbi.nlm.nih.gov/pubmed/1705704
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