Novel synthetic (E)-2-methoxy-4-(3-(4-methoxyphenyl) prop-1-en-1-yl) phenol inhibits arthritis by targeting signal transducer and activator of transcription 3

Rheumatoid arthritis (RA) is a severely debilitating chronic autoimmune disease that leads to long-term joint damage. Signal transducer and activator of transcription 3 (STAT3)-targeted small molecules have shown promise as therapeutic drugs for treating RA. We previously identified (E)-2,4-bis(p-hy...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Son, Dong Ju, Kim, Dae Hwan, Nah, Seong-Su, Park, Mi Hee, Lee, Hee Pom, Han, Sang Bae, Venkatareddy, Udumula, Gann, Benjamin, Rodriguez, Kevin, Burt, Scott R., Ham, Young Wan, Jung, Yu Yeon, Hong, Jin Tae
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5109275/
https://ncbi.nlm.nih.gov/pubmed/27845373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep36852
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