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Mediator binding to UASs is broadly uncoupled from transcription and cooperative with TFIID recruitment to promoters

Mediator is a conserved, essential transcriptional coactivator complex, but its in vivo functions have remained unclear due to conflicting data regarding its genome‐wide binding pattern obtained by genome‐wide ChIP. Here, we used ChEC‐seq, a method orthogonal to ChIP, to generate a high‐resolution m...

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Detalhes bibliográficos
Publicado no:EMBO J
Main Authors: Grünberg, Sebastian, Henikoff, Steven, Hahn, Steven, Zentner, Gabriel E
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5109241/
https://ncbi.nlm.nih.gov/pubmed/27797823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201695020
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