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Mediator binding to UASs is broadly uncoupled from transcription and cooperative with TFIID recruitment to promoters
Mediator is a conserved, essential transcriptional coactivator complex, but its in vivo functions have remained unclear due to conflicting data regarding its genome‐wide binding pattern obtained by genome‐wide ChIP. Here, we used ChEC‐seq, a method orthogonal to ChIP, to generate a high‐resolution m...
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| Udgivet i: | EMBO J |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
John Wiley and Sons Inc.
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5109241/ https://ncbi.nlm.nih.gov/pubmed/27797823 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201695020 |
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