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Clinical validity of detecting circulating tumor cells by AdnaTest assay compared to direct detection of tumor mRNA in stabilized whole blood, as a biomarker predicting overall survival for metastatic castration-resistant prostate cancer patients

Circulating tumor cell (CTC) number measured with the CellSearch(®) assay is prognostic for survival in metastatic castration-resistant prostate cancer (mCRPC) pre- and post-therapy. Using a standard operating protocol for sample collection, processing, and analysis, we compared detection rates of C...

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Publicat a:Cancer J
Autors principals: Danila, Daniel C., Samoila, Aliaksandra, Patel, Chintan, Schreiber, Nicole, Herkal, Amrita, Anand, Aseem, Bastos, Diogo, Heller, Glenn, Fleisher, Martin, Scher, Howard I.
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5108569/
https://ncbi.nlm.nih.gov/pubmed/27749322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/PPO.0000000000000220
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