Pharmacodynamic and Pharmacokinetic Profiles of Sacubitril/Valsartan (LCZ696) in Patients with Heart Failure and Reduced Ejection Fraction

AIMS: Concomitant renin–angiotensin–aldosterone system blockade and natriuretic peptide system enhancement may provide unique therapeutic benefits to patients with heart failure and reduced ejection fraction (HFrEF). This study assessed the pharmacodynamics and pharmacokinetics of LCZ696 in patients...

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Detalhes bibliográficos
Publicado no:Cardiovasc Ther
Main Authors: Kobalava, Zhanna, Kotovskaya, Yulia, Averkov, Oleg, Pavlikova, Elena, Moiseev, Valentine, Albrecht, Diego, Chandra, Priya, Ayalasomayajula, Surya, Prescott, Margaret F., Pal, Parasar, Langenickel, Thomas H., Jordaan, Pierre, Rajman, Iris
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Original Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5108443/
https://ncbi.nlm.nih.gov/pubmed/26990595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/1755-5922.12183
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