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A HIF-1α-driven feed-forward loop augments HIF signalling in Hep3B cells by upregulation of ARNT

Oxygen-deprived (hypoxic) areas are commonly found within neoplasms caused by excessive cell proliferation. The transcription factor Aryl hydrocarbon receptor nuclear translocator (ARNT) is part of the hypoxia-inducible factor (HIF) pathway, which mediates adaptive responses to ensure cellular survi...

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書目詳細資料
發表在:Cell Death Dis
Main Authors: Mandl, M, Lieberum, M-K, Depping, R
格式: Artigo
語言:Inglês
出版: Nature Publishing Group 2016
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5108338/
https://ncbi.nlm.nih.gov/pubmed/27362802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2016.187
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