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A mouse model for investigating the molecular pathogenesis of adenovirus pneumonia.

Intranasal inoculation of type 5 adenovirus (Ad5) produced pneumonia in mice even though the virus did not replicate. To induce the pneumonia, however, a large viral infectious dose was required--i.e., 10(10) plaque-forming units. Four strains of inbred mouse were studied (C57BL/6N, C57BL/10ScN, CBA...

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Detalhes bibliográficos
Main Authors: Ginsberg, H S, Moldawer, L L, Sehgal, P B, Redington, M, Kilian, P L, Chanock, R M, Prince, G A
Formato: Artigo
Idioma:Inglês
Publicado em: 1991
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC51082/
https://ncbi.nlm.nih.gov/pubmed/1848005
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