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Exploiting the dynamic properties of covalent modification cycle for the design of synthetic analog biomolecular circuitry

BACKGROUND: Cycles of covalent modification are ubiquitous motifs in cellular signalling. Although such signalling cycles are implemented via a highly concise set of chemical reactions, they have been shown to be capable of producing multiple distinct input-output mapping behaviours – ultrasensitive...

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Bibliografiske detaljer
Udgivet i:J Biol Eng
Main Authors: Foo, Mathias, Sawlekar, Rucha, Bates, Declan G.
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5108087/
https://ncbi.nlm.nih.gov/pubmed/27872658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13036-016-0036-1
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