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Didox and resveratrol sensitize colorectal cancer cells to doxorubicin via activating apoptosis and ameliorating P-glycoprotein activity

Doxorubicin (DOX) has limited efficacy in colorectal cancer due to multi-drug resistance. Resveratrol (RES) and didox (DID) are polyhydroxyphenols with potential chemosensitizing effects. Herein, we assessed the chemomodulatory effects of RES and DID to DOX in colorectal cancer cells. Equitoxic comb...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Khaleel, Sahar A., Al-Abd, Ahmed M., Ali, Azza A., Abdel-Naim, Ashraf B.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5107943/
https://ncbi.nlm.nih.gov/pubmed/27841296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep36855
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