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Caveolin-1 modulates intraocular pressure: implications for caveolae mechanoprotection in glaucoma

Polymorphisms in the CAV1/2 genes that encode signature proteins of caveolae are associated with glaucoma, the second leading cause of blindness worldwide, and with its major risk factor, intraocular pressure (IOP). We hypothesized that caveolin-1 (Cav-1) participates in IOP maintenance via modulati...

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Dades bibliogràfiques
Publicat a:Sci Rep
Autors principals: Elliott, Michael H., Ashpole, Nicole E., Gu, Xiaowu, Herrnberger, Leonie, McClellan, Mark E., Griffith, Gina L., Reagan, Alaina M., Boyce, Timothy M., Tanito, Masaki, Tamm, Ernst R., Stamer, W. Daniel
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5107904/
https://ncbi.nlm.nih.gov/pubmed/27841369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep37127
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