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Caveolin-1 modulates intraocular pressure: implications for caveolae mechanoprotection in glaucoma

Polymorphisms in the CAV1/2 genes that encode signature proteins of caveolae are associated with glaucoma, the second leading cause of blindness worldwide, and with its major risk factor, intraocular pressure (IOP). We hypothesized that caveolin-1 (Cav-1) participates in IOP maintenance via modulati...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Elliott, Michael H., Ashpole, Nicole E., Gu, Xiaowu, Herrnberger, Leonie, McClellan, Mark E., Griffith, Gina L., Reagan, Alaina M., Boyce, Timothy M., Tanito, Masaki, Tamm, Ernst R., Stamer, W. Daniel
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5107904/
https://ncbi.nlm.nih.gov/pubmed/27841369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep37127
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