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Targeting of slug sensitizes anaplastic thyroid carcinoma SW1736 cells to doxorubicin via PUMA upregulation

Objective: Anaplastic thyroid carcinoma (ATC) is one of the most aggressive human cancers and often shows resistance to multimodal therapeutic approaches. It has been shown that the transcriptional repressor Slug inhibits the chemotherapeutic agent-induced apoptosis of cancer cells. We evaluated whe...

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Bibliografiske detaljer
Udgivet i:Int J Biochem Mol Biol
Main Authors: Dong, Anbing, Jiao, Xuelong, Chen, Dong, Hao, Fengyun, Zhang, Kejun
Format: Artigo
Sprog:Inglês
Udgivet: e-Century Publishing Corporation 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5107651/
https://ncbi.nlm.nih.gov/pubmed/27853625
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