Downregulation of Glutathione Biosynthesis Contributes to Oxidative Stress and Liver Dysfunction in Acute Kidney Injury

Ischemia-reperfusion is a common cause for acute kidney injury and can lead to distant organ dysfunction. Glutathione is a major endogenous antioxidant and its depletion directly correlates to ischemia-reperfusion injury. The liver has high capacity for producing glutathione and is a key organ in mo...

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Detalhes bibliográficos
Publicado no:Oxid Med Cell Longev
Main Authors: Shang, Yue, Siow, Yaw L., Isaak, Cara K., O, Karmin
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5107229/
https://ncbi.nlm.nih.gov/pubmed/27872680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/9707292
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