Cooperative Dynamics of AR and ER Activity in Breast Cancer

Androgen receptor (AR) is expressed in 90% of estrogen receptor alpha positive (ER+) breast tumors, but its role in tumor growth and progression remains controversial. Use of two anti-androgens that inhibit AR nuclear localization, enzalutamide and MJC13, revealed that AR is required for maximum ER...

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Vydáno v:Mol Cancer Res
Hlavní autoři: D’Amato, Nicholas C., Gordon, Michael A., Babbs, Beatrice L., Spoelstra, Nicole S., Carson Butterfield, Kiel T., Torkko, Kathleen C., Phan, Vernon T., Barton, Valerie N., Rogers, Thomas J., Sartorius, Carol A, Elias, Anthony D., Gertz, Jason, Jacobsen, Britta M., Richer, Jennifer K.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5107172/
https://ncbi.nlm.nih.gov/pubmed/27565181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-16-0167
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