Galectin-1 from cancer-associated fibroblasts induces epithelial–mesenchymal transition through β1 integrin-mediated upregulation of Gli1 in gastric cancer

BACKGROUND: Gastric cancer (GC) is characterized by the excessive deposition of extracellular matrix, which is thought to contribute to this tumor’s malignant behavior. Epithelial-mesenchymal transition (EMT) is regarded as a crucial contributing factor to cancer progression. Galectin-1 (Gal-1), a β...

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Detalhes bibliográficos
Publicado no:J Exp Clin Cancer Res
Main Authors: Chong, Yang, Tang, Dong, Xiong, Qingquan, Jiang, Xuetong, Xu, Chuanqi, Huang, Yuqin, Wang, Jie, Zhou, Huaicheng, Shi, Youquan, Wu, Xiaoqing, Wang, Daorong
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
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Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5106768/
https://ncbi.nlm.nih.gov/pubmed/27836001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-016-0449-1
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